Sexual health
PRP and exosome protocols for men's and women's sexual and pelvic-health applications — ED, P-Shot, O-Shot. Recent meta-analyses show meaningful improvement in erectile function over placebo, with the strongest outcomes when PRP is combined with low-intensity shockwave.
- Class
- Sexual · pelvic
- Approach
- Targeted injection
- Materials
- PRP · exosome
- Setting
- In-clinic, brief recovery
01 About
What we treat in this category.
Sexual-health regenerative protocols broadly cover three use cases: erectile dysfunction (ED) in men, decreased sexual function and stress urinary incontinence in women, and post-procedural or post-pelvic-surgery recovery. The most common branded protocols are the P-Shot (Priapus Shot — PRP injection for men) and O-Shot (Orgasm Shot — PRP injection for women).
Standard care for ED is typically PDE5 inhibitors (Viagra, Cialis) and lifestyle modification. Standard care for women's sexual-health concerns is more variable. Regenerative protocols are positioned as an option for patients who are not responding well to standard treatments or want to address the underlying tissue rather than just symptom management.
02 How it works
How regen supports tissue function.
PRP and exosome material delivered to genital tissue support local microvasculature, soft-tissue health, and nerve sensitivity through growth-factor-driven repair. The mechanism is similar to soft-tissue regenerative work elsewhere in the body — applied to a particularly vascular tissue.
For ED in particular, the strongest published outcomes come from combined PRP + low-intensity shockwave protocols. We use the Softwave system to prime the tissue and potentiate the biologic response — the protocol family with the most consistent published efficacy.
03 What the research shows
What the studies show.
The PRP-for-ED evidence base has matured into a clear positive signal — particularly when PRP is paired with low-intensity shockwave. Safety is well-established across all published trials.
PRP Improves Erectile Function: Double-Blind, Randomized, Placebo-Controlled Trial
A double-blind randomized placebo-controlled trial of intracavernosal PRP for ED. At 6 months, 69% of PRP patients met the minimal clinically important difference threshold versus 27% of placebo. PRP was concluded safe and effective for mild-to-moderate ED.
Read on PubMedPRP Alone or Combined with Low-Intensity Shockwave for ED: Meta-Analysis of 7 RCTs
A 2025 systematic review and meta-analysis pooled 7 randomized trials of PRP alone or combined with low-intensity shockwave (Li-SWT). The combination protocol produced the strongest erectile-function gains across the literature — establishing PRP + Li-SWT as the protocol family with the most consistent positive outcomes for vasculogenic ED.
Read on Taylor & FrancisEfficacy of PRP in the Treatment of Erectile Dysfunction
A meta-analysis pooling controlled and single-arm trials of PRP for ED demonstrated significant, dose-dependent improvement in International Index of Erectile Function (IIEF) scores — confirming the efficacy signal across study designs. Safety was uniformly favorable.
Read on PLOS
The protocols with the most consistent outcomes pair PRP injection with low-intensity shockwave — the same combination we run at Apex. We design the protocol around the published evidence, not around marketing claims.
04 Are you a candidate
Who's a candidate.
Candidates:
- Men with mild-to-moderate ED not fully responsive to PDE5 inhibitors.
- Men or women seeking adjunct therapy for sexual-health concerns alongside primary care.
- Women with mild stress urinary incontinence or decreased sexual sensation post-childbirth or post-menopause.
- Vasculogenic ED — the patient subgroup with the strongest published response to PRP + shockwave.
When we will not recommend it:
- Untreated underlying cause (severe vascular disease, hypogonadism, depression).
- Active genital infection or skin condition.
- Patients on anticoagulation that cannot be safely paused for a procedure.
- Patients seeking a guaranteed outcome — that's not what the data supports.
Think you might be a candidate?
The first step is a 60–90 minute consultation. We review your imaging, history, and goals — and tell you honestly whether regenerative therapy is the right next step.
05 A patient experience
Dr. Abdullah is the doctor you'll want to have. Patient, calm, listens attentively. I'll wholeheartedly recommend this place to my family and loved ones.
Mickhail Bobga Google · 5.0
07What happens at your consultation
A conversation, not a sales meeting.
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01
Intake & history
60–90 minutes. We review imaging, prior treatments, current medications, and goals. Most of this hour is listening.
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02
Focused exam
A clinical exam tailored to your indication. Range of motion, strength, functional testing — what the literature actually predicts response on.
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03
Honest candidacy review
If we think you're a candidate, we'll tell you why. If we don't, we'll tell you what we'd recommend instead — surgery, PT, watchful waiting.
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04
Written plan & pricing
A defined treatment plan with modality, sequence, follow-up cadence, and total cost — before any commitment.
06 What treatment looks like
What treatment looks like.
A typical sexual-health protocol begins with consultation, full medical history, and (when appropriate) workup for underlying causes (hormones, vascular health, mental health). Treatment is in-clinic targeted injection — usually a series of two to three sessions spaced over several months. We pair with Softwave shockwave when the evidence supports the combination.
Reassessment at 3 and 6 months. Validated symptom tracking (IIEF for men, FSFI for women) and ongoing coordination with primary care or urology when relevant.
09 Common questions
Common questions, answered.
How is this different from Viagra/Cialis?
PDE5 inhibitors work on demand. Regenerative therapy supports underlying tissue health — vasculature, soft tissue, nerve sensitivity.
Are results immediate?
No. Tissue response builds over weeks to months. 3–6 months is the typical window for meaningful improvement.
Is this just for ED?
No — protocols exist for women's sexual-health and pelvic-floor concerns too. P-Shot for men, O-Shot for women are common branded variants.
Is this safe with my heart medications?
Generally yes. We review your full medication list and coordinate with your primary-care or cardiology team.
How many sessions will I need?
Typically a series of 2–3 in-clinic sessions spaced over months, often paired with low-intensity shockwave.
What are the risks?
Brief post-procedure soreness or bruising is the most common effect. No major adverse events were reported in the published RCTs.
08 Coverage & cost
Most regenerative protocols at Apex are not covered by insurance — we discuss pricing directly, in writing, before any commitment. Softwave shockwave is the exception: covered by Medicare Parts A & B with supplement (not by Medicare Advantage). Financing options are available for protocols not covered. We never hold a pricing conversation until we know you're a candidate.
Begin with a consultation.
A frank conversation about what you're experiencing, what the evidence actually supports, and whether regenerative therapy is the right tool for your situation.